Illumina Layoffs

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Layoff rounds

808

Employees laid off

Post-IPO

Funding stage

$28M

Total raised

Illumina has 9 publicly reported layoff rounds on record between November 14, 2022 and December 22, 2025. A total of about 808 employees were affected across these rounds.

Layoff history

December 22, 2025WARN notice

Illumina cut 1 employee

1 laid off Location San Diego, CA Effective December 22, 2025 Facility 5200 Illumina Way San Diego CA 92122

Illumina disclosed a workforce reduction affecting its San Diego, CA operations in December 22, 2025. Approximately 1 roles were eliminated.

Reason: Layoff Permanent

December 11, 2025WARN notice

Illumina cut 7 employees

7 laid off Location San Diego, CA Effective December 8, 2025 Facility 5200 Illumina Way San Diego CA 92122

Illumina disclosed a workforce reduction affecting its San Diego, CA operations in December 11, 2025. Approximately 7 roles were eliminated.

Reason: Layoff Permanent

December 4, 2025WARN notice

Illumina cut 3 employees

3 laid off Location San Diego, CA Effective February 17, 2026 Facility 5200 Illumina Way San Diego CA 92122

Illumina disclosed a workforce reduction affecting its San Diego, CA operations in December 4, 2025. Approximately 3 roles were eliminated.

Reason: Layoff Permanent

November 20, 2025WARN notice

Illumina cut 7 employees

7 laid off Location San Diego, CA Effective January 19, 2026 Facility 5200 Illumina Way San Diego CA 92122

Illumina disclosed a workforce reduction affecting its San Diego, CA operations in November 20, 2025. Approximately 7 roles were eliminated.

Reason: Layoff Permanent

November 6, 2025WARN notice

Illumina cut 28 employees

28 laid off Location San Diego, CA Effective January 5, 2026 Facility 5200 Illumina Way San Diego CA 92122

Illumina disclosed a workforce reduction affecting its San Diego, CA operations in November 6, 2025. Approximately 28 roles were eliminated.

Reason: Layoff Permanent

February 1, 2024

Illumina cut 111 employees

111 laid off Location San Diego

Illumina disclosed a workforce reduction affecting its San Diego operations in February 1, 2024. Approximately 111 roles were eliminated.

Source: sandiegouniontribune.com

August 17, 2023

Illumina cut 151 employees

151 laid off Location San Diego

Illumina disclosed a workforce reduction affecting its San Diego operations in August 17, 2023. Approximately 151 roles were eliminated.

Source: sandiegouniontribune.com

June 21, 2023

Illumina cut staff

Location San Diego

Illumina disclosed a workforce reduction affecting its San Diego operations in June 21, 2023.

Source: sec.gov

November 14, 2022

Illumina cut 500 employees (5% of staff)

500 laid off 5% of workforce Location San Diego

Illumina disclosed a workforce reduction affecting its San Diego operations in November 14, 2022. Approximately 500 roles were eliminated.

Source: genomeweb.com

Data for Illumina is compiled from public WARN Act filings and reporting linked above. See our methodology.